Clinical Study | News
Rethinking Equine Stifle Injuries: Surprising Insights from a New Study
Written by : Renovo Equine

Rethinking Equine Stifle Injuries: Surprising Insights from a New Study

The research, conducted by Esselman et al., analyzed the recovery outcomes of 34 western performance horses diagnosed with chondromalacia—softening of the articular cartilage in the stifle joint. The study aimed to determine whether the severity and distribution of the condition or postoperative therapy choices influenced a horse’s ability to return to work.

The researchers divided the horses into four severity categories (slight, mild, moderate, or marked) based on arthroscopic findings. They also examined the effectiveness of three postoperative treatment approaches:

  • Bone marrow-derived mesenchymal stem cells (BM-MSCs)
  • Equine amniotic allograft product
  • No postoperative therapy

Outcome success was measured on a numeric scale (1–10), with higher scores indicating a greater return to prior levels of athletic performance.

Key Findings

Surprisingly, the study found no significant correlation between the severity of chondromalacia and a horse’s ability to return to work. Additionally, the type of postoperative intra-articular therapy did not statistically impact the return-to-performance rate. Here are some of the key takeaways:

  • Severity of Chondromalacia Does Not Dictate Recovery: Unlike previous assumptions that more severe cases would have a poorer prognosis, the study showed that severity had no statistically significant effect on whether a horse resumed athletic activity.
  • 74% of Horses Returned to Some Level of Work: This figure represents a more favorable outcome than previously reported, suggesting that even horses with diagnosed chondromalacia have a fair chance of returning to work.
  • Postoperative Therapy Choices Were Not Predictive of Outcome: Whether horses received BM-MSCs, equine amniotic allografts, or no additional therapy, their chances of returning to performance remained similar. However, individual cases may still benefit from regenerative therapies based on the veterinarian’s discretion.

Clinical Significance

This study provides veterinarians and horse owners with valuable insights into treatment expectations for western performance horses with stifle injuries. While intra-articular therapies remain widely used in equine medicine, this research suggests that the overall prognosis may be more favorable than previously believed, regardless of treatment type.

Veterinarians can now approach chondromalacia cases with a more optimistic outlook, focusing on individualized rehabilitation and recovery plans rather than relying solely on severity assessments or specific postoperative interventions.

Ultimately, this research highlights the importance of comprehensive care strategies and continued advancements in equine medicine. As our understanding of equine joint health evolves, veterinarians and horse owners can make more informed decisions that support long-term soundness and performance.

For more details, you can access the full study here:

Severity, Distribution and Postoperative Therapy Are Not Predictors of Return to Work in Western Performance Horses With Stifle Chondromalacia

Other Clinical Studies

RenoVō® CASE STUDY: Puncture Wound

RenoVō® CASE STUDY: Puncture Wound

Case presentation - June 9, 2022: A three-year-old Quarter Horse filly backed into the catch for the stall door and punctured herself, creating a large, deep wound on her left thigh. The wound was sutured with internal and external stiches at clinic, however the...

RenoVō® CASE STUDY: Superficial Digital Flexor Tendon (RH)

RenoVō® CASE STUDY: Superficial Digital Flexor Tendon (RH)

Case presentation - June 9, 2016: A 9 year old Warmblood jumping horse presented with a superficial digital flexor tendon injury of the right hind leg. The horse was treated with stem cell injections. After 10 months of rest and rehabilitation, the horse slowly went...

RenoVō® CASE STUDY: Summer Sore

RenoVō® CASE STUDY: Summer Sore

Case presentation - June 17, 2022: A 19-year-old Red Horse presented to Topgun Veterinarian Service, Rock Hill, SC, with a large Summer Sore on the commissure of the right side of the mouth. The horse was treated orally with Ivermectin and topically with Ivermectin...

See all Clinical Studies